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Friday 01 April 2005

[Susceptibility to norfloxacin of some bacterial strains causing urinary infections]

By: Tuchilus C, Poiata A, Badicut I, Buiuc D.

Rev Med Chir Soc Med Nat Iasi 2005 Apr-Jun;109(2):383-6

The purpose of this study was to evaluate the in vitro activity of norfloxacin in comparison with ofloxacin, pefloxacin and ciprofloxacin against 662 strains. The studied strains were obtained from urine, during 2003 period, in Eastern region of Romania. The minimum inhibitory concentrations (MICs) were determined on Mueller-Hinton agar by the dilution technique, with an inoculum of 10(5) CFU/spot. Among tested quinolones, norfloxacin has the better activity against tested strains. The fluoroquinolone compounds were very potent against Escherichia coil strains. Our data shown the spread of quinolone resistance in our area and demonstrated the necessity of adequate antibiotic use in the hospital and community.

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